Molecular Details
DICL_CP_0306975
- zinc(2+)
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0306975
PubChem CID
Molecular Formula
Zn+2 Molecular Weight
65.39 g/mol
Synonyms/Alias
[zinc ion; zinc(2+); Zinc cation; 23713-49-7; Zinc; ion (Zn2+); zinc(II); Zn2+; Velmanase Alfa; Topostin B; 9025-42-7; Zinc(2+)ions; Zinc ion(2+); Zinc 2+; Lamazym; Rhlaman; Velmanase Alfa [INN]; zinc...
InChI Key
PTFCDOFLOPIGGS-UHFFFAOYSA-N
InChI
InChI=1S/Zn/q+2
IUPAC Name
zinc(2+)
CAS Number
1314-13-2
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
1 0 0 0 0 0 0 0 0 0999 V2000
0.0000 0.0000 0.0000 Zn 0 0 0 0 0 15 0 0 0 0 0 0
M CHG 1 1 2
M END
$$$$
Experimental Data
Activity Data
Target Ion Channel
Voltage-gated proton channel (Hv1)
Uniprot Accession Number
Function
Inhibitor
Species
Homo sapiens (Human)
IC50
IC50: 680000 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.4
Holding Potential
Not specified
Temperature
Not mention
Test Method
Fluorometric Imaging Plate Reader (FLIPR) Membrane Potential Assay
Test Species
HEK293T cell (Homo sapiens embryonic kidney 293T cell)
Binding Information
Binding Site
Extracellular domain
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
1
Rotatable Bonds
0
logP
-0.0025
Complexity
2.5
TPSA (Ų)
0
H-Bond Donors
0
H-Bond Acceptors
0
Ring Count
0